7 Best Perioral Dermatitis Toothpastes: Top Picks I Swear By

I came across Toms Kids Strawberry Toothpaste on Reddit, where someone with severe perioral dermatitis said they had tried everything, and this was the only toothpaste that helped them. It’s fluoride-free, SLS-free, and non-toxic, making it a super gentle option for anyone looking to eliminate common triggers. Plus, the strawberry flavor is a nice bonus—no harsh minty burn, just a mild, easy-on-the-teeth formula. If you’re struggling with PD and haven’t looked into your toothpaste, this might be worth a try!

I first came across RiseWell Mineral Toothpaste through a TikTok recommendation, and after looking into it, I had to give it a try. Unlike conventional toothpastes that rely on fluoride, this one uses hydroxyapatite—a naturally occurring mineral that helps strengthen enamel and remineralize teeth. It’s also completely free of SLS, artificial flavors, and other potential irritants, making it a great option for anyone with perioral dermatitis or sensitive skin.

After using it for a while, I can confidently say that it feels just as effective as traditional toothpaste, but without the harsh ingredients. The texture is smooth, it foams up just enough, and the taste is mild—not overpowering like some natural toothpastes tend to be. The only potential downside? It’s a little pricey compared to your standard drugstore options, but if you’re looking for a non-toxic, skin-friendly toothpaste that actually supports oral health, I think it’s worth it.

I first heard about Davids Toothpaste through the clean beauty community—people raving about its fluoride-free formula, sleek aluminum packaging, and high-quality ingredients. Since I’ve been on a mission to swap out anything that could trigger my perioral dermatitis, I decided to give it a shot.

What I Loved About Davids Toothpaste:

✅ Fluoride-Free & SLS-Free – A must for me, since SLS (sodium lauryl sulfate) is known to cause irritation and can be a big trigger for PD.
✅ Nano-Hydroxyapatite (n-Ha) for Enamel Strengthening – This is a non-toxic alternative to fluoride that actually helps remineralize teeth, making them stronger over time.
✅ Clean Ingredients – No artificial sweeteners, preservatives, or unnecessary fillers. It’s also EWG-certified, which is a plus.
✅ Tastes Good (But Not Overpowering) – I tried the Peppermint flavor, and it’s minty without that burning sensation some conventional toothpastes have. It also comes in a charcoal and herbal citrus mint version.
✅ Eco-Friendly Packaging – The tube is made of recyclable aluminum , and they include a key to help squeeze out every last bit of product.

What I Didn't Love:

❌ The Texture Takes Getting Used To – It’s slightly thicker and doesn’t foam up like conventional toothpaste (since it’s SLS-free). This isn’t a dealbreaker, but it took me a few uses to adjust.
❌ More Expensive Than Drugstore Options – At around $10-$12 per tube , it’s pricier than something like Tom’s of Maine, but it lasts a long time and has better ingredients.
❌ Not as Intense of a "Clean" Feeling – Because it doesn’t have the artificial foaming agents most people are used to, some might feel like their teeth aren’t as squeaky clean (even though they actually are).

My final thoughts: If you’re looking for a clean, fluoride-free toothpaste that actually supports enamel health, Davids is a solid choice. The nano-hydroxyapatite is a huge plus for strengthening teeth, and the ingredient list is one of the cleanest I’ve seen. It’s definitely pricier, but if you care about what’s in your toothpaste, it’s worth it.

Happy Toothpaste in Orange Citrus is a great fluoride-free, SLS-free option for those with perioral dermatitis . It’s gentle on sensitive skin, non-toxic, and free from artificial flavors and preservatives. The mild, refreshing citrus flavor is non-irritating, and the formula lathers well without harsh chemicals. A solid choice for those seeking a gentle, PD-friendly toothpaste.

20,000 people purchased these in the past month! No BS Toothpaste Tablets are a game-changer, especially for those with perioral dermatitis. These tablets are SLS-free, fluoride-free, and have minimal ingredients, making them a great option for sensitive skin. They’re super easy to use—just pop a tablet in your mouth, chew it, and brush. I love how they’re mess-free, travel-friendly, and still manage to leave your mouth feeling fresh. While they don’t foam like traditional toothpaste, they still get the job done without irritating sensitive skin. Definitely a solid choice for anyone looking for a clean, simple option!

Boka’s toothpaste is a standout for perioral dermatitis because it’s fluoride-free, SLS-free, and made with clean ingredients. Plus, it’s non-toxic, so it's perfect for anyone looking for a gentle option that still works. My personal favorite flavor is Coco Ginger—it’s refreshing without being overpowering. It’s also kid-friendly, which is a bonus if you’re trying to keep the whole family on the same page with their oral care. If you're looking for a soothing, effective toothpaste, Boka is definitely worth trying!

Jason's Toothpaste was the toothpaste I used when my perioral dermatitis was really flaring up, and it helped a lot. It has a mild coconut mint flavor, which was refreshing but not too overpowering, and it felt like it was really cleaning my teeth without triggering my PD. The best part? It’s super affordable at just $7 per bottle, which is a win. 

The only downside I found was that, over time, it made my teeth a bit sensitive. But if you're looking for a budget-friendly option that’s gentle on your PD and effective for your teeth, Jason’s is definitely worth considering.